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Figure 1 | Journal of Nanobiotechnology

Figure 1

From: Formulation of polylactide-co-glycolic acid nanospheres for encapsulation and sustained release of poly(ethylene imine)-poly(ethylene glycol) copolymers complexed to oligonucleotides

Figure 1

Characterization of 72 kDa lauryl ester end-capped PLGA nanospheres with and without encapsulated PEG-PEI-AO polyplexes or AO alone. (A) Mean diameter determined by DLS. PLGA nanospheres loaded with PEG-PEI-AO polyplex were significantly larger than those loaded with AO alone or unloaded samples (*P = .0079). (B) Polymer yields calculated based on the weight of the resultant nanospheres and initial mass of PLGA and encapsulant. (C) Encapsulation efficiency (EE). Three separate samples were evaluated for each group.

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