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Table 1 Evaluation of the dual-label TRF assay for simultaneous detection of HIV-1 and HBV infections

From: Simultaneous detection of Human Immunodeficiency Virus 1 and Hepatitis B virus infections using a dual-label time-resolved fluorometric assay

Grp

n

Infection profile

(Ref assay)a

Dual-label assay

(HIV-1+/HBV+)b

In-house sera panel

1

25

HIV-1-/HBV+

0/23c

2

12

HIV-1+/HBV-

12/0

BBI co-infection panel

3

13

HIV-1+/HBV+

13/10d

4

6

HIV-1-/HBV+

0/6

5

3

HIV-1+/HBV-

3/0

6

1

HIV-1-/HBV-

0/0

  1. a The Reference assays for the in-house sera panel were Vidas HIV Duo Quick and HBsAg Ultra assays, for anti-HIV-1 antibody and HBsAg detection, respectively; the Reference assays for the BBI co-infection panel are mentioned in the Supplementary Information (see Additional file 1). The "+" and "-" superscripts indicate positive and negative tests, respectively.
  2. b This column indicates the results obtained using the dual-label assay described in the text. The numbers shown indicate the serum samples that scored positive for both analytes in the dual-label assay.
  3. cmissed two HBsAg+ serum samples
  4. dmissed three HBsAg+ serum samples