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Figure 1 | Journal of Nanobiotechnology

Figure 1

From: Enzymatic- and temperature-sensitive controlled release of ultrasmall superparamagnetic iron oxides (USPIOs)

Figure 1

Synthesis of PEG-PPS-based polymer-biomolecule conjugates. The PPS block is formed by anionic ring-opening polymerization of an episulfide monomer, and endcapped with methyl acrylate. Conversion of the terminal methyl ester group to a carboxylic acid is accomplished under highly basic conditions to enable subsequent coupling of a PEG block and then a biofunctional ligand (e.g., peptides, amine-functionalized ssDNA) in modular fashion, yielding PEG-PPS-based polymer-biomolecule conjugates.

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