Figure 8

Enhanced clonal expansion capacity of hBM-MSCs in the presence of conjugated FGF2. Human BM-MSCs were seeded in 6 well plates and incubated in growth media alone (control) or growth media supplemented with 50 ng/ml free or conjugated FGF2, or free NPs. Media was change every 3 days. Seven days post seeding, colonies were counted following extensive washing and Giemsa staining. Data is presented as fold increase in colony number compared with control (mean ± SE of 3 experiments in duplicates or triplicates using cells from 3 different donors).