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Table 1 Compositions of NLC formulations used in the optimization experiments [U*7(74) uniform experimental design]

From: Nanostructured lipid carriers for percutaneous administration of alkaloids isolated from Aconitum sinomontanum

NLCs

Factor A (X1)

Factor B (X2)

Factor C (X3)

Factor D (X4)

Drug content

Lipid (%)

Surfactant (%)

Solid/liquid (w/w)

Drug/lipid (w/w)

(%, w/v)

NLC1

2

4

1:1.5

1:30

0.07

NLC2

4

6

2:1

1:25

0.16

NLC3

6

8

1:2

1:20

0.30

NLC4

8

3

1.5:1

1:15

0.53

NLC5

10

5

1:3

1:10

1.00

NLC6

12

7

1:1

1:5

2.40

NLC7

14

9

3:1

1:35

0.40

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Journal of Nanobiotechnology

ISSN: 1477-3155

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