Fig. 2

Monomeric building block and computer models of complete SAPNs. Top: monomeric building block composed of a His-tag sequence (black), a pentameric domain based on Trp-zipper (green) and a shortened trimeric de novo designed coiled-coil domain (blue). Bottom Computer models of the complete peptide nanoparticle with a diameter of roughly 21 nm. The black region (His-tag) is a random coil, which could be fully extended giving a diameter of roughly 27 nm. a 2HR, b 2.5HR and c 3HR