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Table 4 Enzymatic activity of the key players of cellular antioxidative defence

From: Glucose availability determines silver nanoparticles toxicity in HepG2

Enzyme

Activity (u/mg protein)

25 mM glucose

5.5 mM glucose

Catalase

75.19 ± 6.62

89.81 ± 7a

Glutathione S–transferase

0.97 ± 0.16

1.64 ± 0.26a

Superoxide dismutase

582 ± 75.2

803 ± 87.5a

Glutathione reductase

9.21 ± 1.59

12.94 ± 1.19a

  1. Enzyme activities were compared with t test (n = 4, α = 0.05)
  2. aDenotes statistical important difference between HepG2 cells cultured on high glucose medium and low glucose medium for 30 days. Values represent means with standard deviation