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Table 1 Gold concentrations in different brain regions following AuNP injection with and without perfusion

From: Spontaneous penetration of gold nanoparticles through the blood brain barrier (BBB)

Organ

Perfusion (N = 4)

No perfusion (N = 2)

Frontal cortex

0.63 ± 0.27

6.21 ± 4.69

Hippocampus

0.56 ± 0.39

3.19 ± 3.45

Hypothalamus

0.31 ± 0.16a

4.56 ± 5.12

  1. Gold concentrations (μg/g/mg gold injected) measured in different brain regions following AuNP injection with and without perfusion. To allow comparison between the results of the different experiments, the data were normalized to the amount of gold injected in each experiment
  2. aA single high concentration value defined as an outlier was omitted. If this value is included the gold concentration found in the hypothalamus is 3.2 ± 5.2 μg/g/mg gold injected