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Table 4 Determination of the accuracy, sensitivity and specificity of the in vitro NR8383 alveolar macrophage assay

From: An in vitro alveolar macrophage assay for predicting the short-term inhalation toxicity of nanomaterials

 

Test material activity, STIS

Test material passivity, STIS

SUM

 

Test material activity, in vitro

9

1

10

90 % positive prediction

Test material passivity, in vitro

0

10

10

100 % negative prediction

SUM

9

11

20

 
 

100 % sensitivity

91 % specificity

 

Accuracy 95 %

 
  1. Comparison of altogether 20 in vitro test results (cf. Table 3) to in vivo results from rat short-term inhalation studies applying the Cooper statistics [93]
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Journal of Nanobiotechnology

ISSN: 1477-3155

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