Fig. 5

The ROI is set in a black square in the T2* signal reduction region (a). Fluorescent images of the ischemic brain section in the targeting area (b–d). SR-FLIVO expression (b) and TUNEL immunopositivity (c) were co-localized as shown in the merged image (d). Bar 20 μm. e–g Electron micrographs demonstrated no localization of SR-FLIVO-FMNP probe inside control cell in non-ischemic core, whereas, it was localized within apoptotic cell in the ischemic core. Arrows point to the FMNP conjugated SR-FLIVO (g). Bar 500 nm for e and f and 100 nm for g