Fig. 4
From: Influence of PapMV nanoparticles on the kinetics of the antibody response to flu vaccine
PapMV nanoparticles increase the proportion of germinal centers in the late response in TIV vaccinated mice, a Draining lymph nodes of mice immunised with TIV supplemented with PapMV or TIV alone were collected at different time points post-immunization (3, 5, 7, 10 and 14 days). Germinal centers (PNAhi and GL7hi) were assayed among CD45R+ cells by flow cytometry, b Spleen labelled with CD45R and PNA specific antibodies revealed that animals vaccinated with TIV + PapMV nanoparticles show larger germinal centers as compared to the control groups.