Fig. 3

Light micrographs of parts of hepatic lobules at 1 h-control (a, c, e), rGO-15 min (b) and 7 days—rGO treated rats (d, f). Representative photomicrographs of the hepatic parenchyma stained with Hematoxylin-eosin (a, b); treated for immunostaining of anti-caspase 9 (c, d) and stained with Masson’s trichrome staining for detecting collagen type 1 in normal (e) and rGO-treated (f) tissue. Insets depict collagen fibers around the blood vessels. pv portal vein; cv central vein. Bars 100 µm