Skip to main content

Table 1 Summary of clinical signs and behavioral response destined to evaluate neurotoxicity before and after rGO i.v administration (7 mg/kg)

From: Reduced graphene oxide: nanotoxicological profile in rats

Autonomic nervous system

Peripheral nervous system (neuromuscular)

Behavioral (activity)

Central nervous system (excitability)

Lacrimation

Righting reflex

Motor activity

Clonic movements

Salivation

Hindlimb grip strength

Home cage posture

Tonic movements

Excretion

Forelimb grip strength

Rearing

 

Piloerection

   
  1. All the parameters evaluated in rGO-treated rats showed no discrepancy relative to the observed in rats treated with vehicle (control)
  2. n = 3–5 per time of sampling; n = 5 control group