Table 1 Physicochemical characterization of Lipidots
Lipid (mg/mL) | Numberof particles/mL | MTHPC molecules/particle | mTHPC (µg/mL) | Drug loadinga | Hydrodynamic diameter (nm) | Poly-dispersity index | |
|---|---|---|---|---|---|---|---|
50 nm M-Lipidot | 50 | 7.27565 × 1014 | ~920 | 722 | 2.8 % | 47.7 ± 1.1 | 0.153 ± 0.01 |
120 nm M-Lipidot | 50 | 5.26306 × 1013 | ~4600 | 262 | 1.0 % | 111.2 ± 2.2 | 0.103 ± 0.01 |
50 nm Lipidotb | 50 | 7.27565 × 1014 | – | – | – | 49.5 ± 1.5 | 0.170 ± 0.07 |
120 nm Lipidotb | 50 | 5.26306 × 1013 | – | – | – | 95.4 ± 3.4 | 0.120 ± 0.05 |