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Fig. 6 | Journal of Nanobiotechnology

Fig. 6

From: Anthocyanins encapsulated by PLGA@PEG nanoparticles potentially improved its free radical scavenging capabilities via p38/JNK pathway against Aβ1–42-induced oxidative stress

Fig. 6

Schematic representation of intracellular uptake of anthocyanin loaded PEGylated NPs by SH-SY5Y cell via endocytosis; inside the cellular cytoplasm, the endosome is broken down by lysosomal enzymes and the drug is released in the cytoplasm and reverts the Aβ1–42-induced Aβ pathology by abrogating ROS generation via the P38-MAPK/JNK pathways accompanied by induction of endogenous nuclear factor erythroid 2-related factor 2 (Nrf2) and heme oxygenase 1 (HO-1)

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Journal of Nanobiotechnology

ISSN: 1477-3155

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