Fig. 3
Impact of PLA-NP on cytokine secretion. a Graphs showing the effects of PLA-NP at different concentrations (2, 20 and 200 µg/mL) in A549 cells after 24, 48 and 72 h upon IL-12p70, VEGF, IL-15 and IL-10 levels. b Heat graph showing all secreted products analyzed after 20 µg/mL PLA-NP treatment during 24, 48 and 72 h. ‘+C’ means positive control corresponding to A549 cells treated with 20 ng/mL TNFα for 24 h. Each experimental group corresponds to the analysis of three independent experiments. One-way ANOVA test with Bonferroni’s multiple comparisons test compared to respective Control group (*p < 0.05)