Fig. 5
From: Development of nanoparticle-based optical sensors for pathogenic bacterial detection
(Reprinted with permission from [79]. Copyright 2011 American Chemical Society)
a Representat ion of trans-cyclooctene (TCO) derivatives of daptomycin binding to Gram-positive bacteria. Ca2þ channels control the process of oligomerization and binding to the cell surface results in the format ion of pores in the peptidoglycan layer. b Dapt-TCO derivatives detected using high-performance liquid chromatography and elect rosprayionization mass spectrometry. c Fluorescence spectrometry of bacterial cells stained with various concent rations of Dapt-TCO and labeled with magnet of luorescent nanoparticles (data expressed as mean and standard deviation). d Bacteria tracking by magnetic resonance (data expressed as mean and standard error)