Fig. 2
From: Vectorized nanodelivery systems for ischemic stroke: a concept and a need
(Reproduced from [107] by permission of Stroke)
a Molecules expressed in a rat ischemia–reperfusion model. Temporal expression of heat shock protein-72 (colour-coded density maps overlaid on magnetic resonance images). The highest expression level is found in the cerebral cortex between 6 and 12 h after occlusion. b Temporal expression of glutamate (colour-coded spectroscopic maps). The maximum concentration occurs at 30 min following occlusion at the nucleus of the lesion, while the peak glutamate concentration in the periphery of the infarction occurs at 6 h after occlusion