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Scheme 1 | Journal of Nanobiotechnology

Scheme 1

From: Polymeric micelles with dual thermal and reactive oxygen species (ROS)-responsiveness for inflammatory cancer cell delivery

Scheme 1

Illustration of the stimuli-responsiveness of PPS-PNIPAm block copolymer. a Oxidation-responsiveness of PPS block and temperature-responsiveness of PNIPAm block. b Self-assembling of PPS-PNIPAm micelles and loading with doxorubicin. The PNIPAm corona undergoes shrinkage and collapse above its LCST and PPS core can be furtherly oxidised and release encapsulated DOX molecules. Such drug-loaded nanocarrier can be used in cancer cell delivery and release drug in ROS intracellular environment

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