Fig. 3

TEM cross section of ADSCs exposed to TiO₂ NPs in different conditions: in basal media (a–f), after 3 weeks in adipose induction media (g–l). ADSC control cells in basal media (a), ADSCs exposed to 0.4 mg/mL anatase (b) and 0.4 mg/mL rutile (c) for 3 days in basal media. ADSC control in basal media high magnification (d), ADSCs exposed to 0.4 mg/mL anatase (e) and 0.4 mg/mL rutile (f) for 3 days in basal media high magnification. ADSC control cells in induction media (g) for 3 weeks, ADSCs exposed to 0.4 mg/mL anatase (h) and 0.4 mg/mL rutile (i) for 3 weeks. ADSC control cells in induction media high magnification (j), ADSCs exposed to 0.4 mg/mL anatase (k) and 0.4 mg/mL rutile (l) in induction medium for 3 weeks high magnification. Black arrows indicate the vacuoles (a–f) and lipid droplets (g–l)