From: Distribution of PLGA-modified nanoparticles in 3D cell culture models of hypo-vascularized tumor tissue
Spheroid cross-sectional area (mm2)
Cell line
Hanging drop
Liquid overlay
HeLa
0.31 ± 0.02
0.55 ± 0.03
CaSki
0.10 ± 0.02
0.39 ± 0.04
SiHa
0.25 ± 0.03
0.57 ± 0.04