Table 4 NP distribution in terms of maximum mean fluorescence intensity (MFI) observed at a given penetration depth (μm) for each spheroid (LO or HD) and tumor cell type, relative to NP treatment group
Maximum penetration peak (MFI, μm) | ||||
|---|---|---|---|---|
Cell line | Unmodified NPs | MPG NPs | PEG NPs | Co-treatment NPs |
HeLa | LO (54, 78) HD (99, 85) | LO (123, 76) HD (225, 129) | LO (42, 203) HD (217, 82) | LO (133, 150) HD (154, 102) |
CaSki | LO (76, 38) HD (83, 52) | LO (89, 35) HD (101, 66) | LO (62, 39) HD (135, 64) | LO (64, 73) HD (84, 90) |
SiHa | LO (72, 79) HD (123, 61) | LO (66, 88) HD (222, 91) | LO (151, 107) HD (238, 78) | LO (120, 52) HD (239, 84) |