Fig. 3
From: Ions doped melanin nanoparticle as a multiple imaging agent
Specific targeting of the red-fluorescent iMNP after EGFR antibody conjugation (a, blue: DAPI nuclear staining and red: iMNP-EGFR, scale bar: 20 μm). Bio-TEM image of EGFR positive HepG2 liver cancer cell morphology after treatment with iMNP-EGFR (a, right, scale bar: 1 μm, N indicates the nucleus). Cellular phantom study data of the T 1-w MR and CT imaging after treatment and accumulation of cells by centrifugation (see “Methods”) to confirm selectivity (b)