Fig. 6
A Oxidization stress and pH triggered PTX drug release profiles from PTX-loaded P4 copolymer micromicelles at 37 °C and various pH and H2O2 concentrations: (a) pH 7.4, (b) pH 6.3, (c) pH 5.3, (d) pH 5.3 and 0.2% H2O2, and (e) pH 5.3 and 0.8% H2O2, and free PTX release at medium of (f) pH of 7.4 and (g) pH of 5.3 and H2O2 of 0.8%; and B cytotoxicity of (a) free PTX, (b) blank P4 and (c) PTX-loaded P4 micromicelles at pH 7.4, and (d) PTX-loaded P4 micromicelles at pH of 5.3 and a H2O2 concentration of 0.8% against A549 lung cancer cell lines at 37 °C after 24 h incubation