Fig. 7
From: Dual-drug loaded nanoneedles with targeting property for efficient cancer therapy
Anticancer effects of different formulations. A Volume change of tumor in mice during the treatment. B Weights of HeLa tumors after being treated by different (nano)formulations. C Weight change of the tumor-bearing mice during the treatment. D Histological section of the tumor of the mice after the treatment. (a) 0.9% NaCl aqueous solution, (b) free HCPT and MTX, (c) NDs + free MTX, and (d) DDNDs. All HCPT-MTX formulations used the same concentration of HCPT and MTX in mice bearing HeLa tumor. *P < 0.05