Synergistic mechanism of Ag+–Zn2+ in anti-bacterial activity against Enterococcus faecalis and its application against dentin infection

Table 2 Antibacterial efficiency of Ag⁺–Zn²⁺ combinations based on growth curve determination

Atomic ratio (Ag⁺–Zn²⁺)	AgNO₃ + Zn(NO₃)₂·6H₂O (× 10⁻² mg/mL)		Antibacterial efficiency (Median (P25–P75) [%])
Atomic ratio (Ag⁺–Zn²⁺)	1 × 10⁶ CFUs/mL	1 × 10⁸ CFUs/mL	1 × 10⁶ CFUs/mL	1 × 10⁸ CFUs/mL
1:1	1.6 + 2.8	3.2 + 5.6	111.68 (106.09–113.65)	104.92 (104.10–106.53)
1:3	1.6 + 8.4	3.2 + 16.8	123.58 (113.85–126.03)	109.43 (106.16–115.32)
1:6	1.6 + 16.8	3.2 + 33.6	155.21 (142.46–155.90)^a	181.98 (172.57–191.55)^a
1:9	1.6 + 25.2	3.2 + 50.4	165.85 (155.98–167.69)^a	189.38 (186.85–190.60)^a
1:12	1.6 + 33.6	3.2 + 67.2	166.27 (150.97–167.80)^a	188.99 (188.67–189.05)^a

Groups designated by same superscript are not significantly different (p > 0.05)

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