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Fig. 8 | Journal of Nanobiotechnology

Fig. 8

From: ROS responsive resveratrol delivery from LDLR peptide conjugated PLA-coated mesoporous silica nanoparticles across the blood–brain barrier

Fig. 8

The effect of RSV released from LPMSNPs on PMA activated microglia. a The expression of NADPH p47phox and Iba-1 by immunofluorescence assay. PMA activates NADPH p47phox and up-regulates Iba-1 in HAPI microglia cells and increase superoxide production, which could be reduced by RSV. b The quantitive analysis of mean fluorescence intensity. *p < 0.05 vs control; #p < 0.05 vs only PMA stimulation

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