Fig. 6
From: Targeting HER2-breast tumors with scFv-decorated bimodal nanoprobes
In vivo tumor targeting with SPIONs-Cy-PEG-scFv. a In vivo MR tumor imaging with SPIONs-Cy-PEG and SPIONs-Cy-PEG-scFv in BT-474 tumor-bearing mice (ectopic tumors were encircled for better clarity). b Quantification of grey level intensity in tumor after IV injection of SPIONs-Cy-PEG (blue line; n = 5) and SPIONs-Cy-PEG-scFv (red line; n = 4) (11.7 mg/kg Fe body weight) and according time. *p < 0.05, **p < 0.01 (student t-test)