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Table 5 Paclitaxel and curcumin combination index (CI) against MCF-7 and MCF-10A cells

From: Paclitaxel and curcumin coadministration in novel cationic PEGylated niosomal formulations exhibit enhanced synergistic antitumor efficacy

Combination type

MCF-7 cells

MCF-10A cells

CI

Interaction type

CI

Interaction type

Free paclitaxel + free curcumin solution

0.23

Synergistic

0.53

Synergistic

Paclitaxel niosome + curcumin niosome

0.35

Synergistic

0.53

Synergistic

  1. CI < 1, synergistic; CI = 1, additive; CI > 1, antagonistic