Table 1 Effect of different ratios of KTN to KOS on the characteristics of AMO-loaded KNPs (mean ± SD; n = 3)
From: Development of keratin nanoparticles for controlled gastric mucoadhesion and drug release
Formulation | AMO (%) | Size | Zeta potential (mV) | ||
|---|---|---|---|---|---|
LC | EE | nm | PDI | ||
KNP-1 (100/0) | 15.73 ± 0.44 | 62.65 ± 1.99 | 395.3 ± 21.5 | 0.240 ± 0.020 | 14.25 ± 0.23 |
KNP-2 (75/25) | 11.01 ± 1.03 | 59.49 ± 0.83 | 370.0 ± 19.6 | 0.300 ± 0.077 | 9.74 ± 0.15 |
KNP-3 (50/50) | 9.89 ± 0.16 | 53.01 ± 2.11 | 354.6 ± 20.9 | 0.251 ± 0.042 | 7.65 ± 0.27 |
KNP-4 (25/75) | 8.88 ± 1.20 | 49.96 ± 0.98 | 345.5 ± 15.3 | 0.242 ± 0.050 | − 3.23 ± 0.41 |