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Table 1 Effect of different ratios of KTN to KOS on the characteristics of AMO-loaded KNPs (mean ± SD; n = 3)

From: Development of keratin nanoparticles for controlled gastric mucoadhesion and drug release

Formulation AMO (%) Size Zeta potential (mV)
LC EE nm PDI
KNP-1 (100/0) 15.73 ± 0.44 62.65 ± 1.99 395.3 ± 21.5 0.240 ± 0.020 14.25 ± 0.23
KNP-2 (75/25) 11.01 ± 1.03 59.49 ± 0.83 370.0 ± 19.6 0.300 ± 0.077 9.74 ± 0.15
KNP-3 (50/50) 9.89 ± 0.16 53.01 ± 2.11 354.6 ± 20.9 0.251 ± 0.042 7.65 ± 0.27
KNP-4 (25/75) 8.88 ± 1.20 49.96 ± 0.98 345.5 ± 15.3 0.242 ± 0.050 − 3.23 ± 0.41