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Table 3 Peak areas of SC lipids and keratin protein of skin samples with different treatment

From: Lipid nanoparticles loading triptolide for transdermal delivery: mechanisms of penetration enhancement and transport properties

Samples

Lipids

Keratin protein

νas CH2

νs CH2

νs C=O

Amide I

Amide II

Control

23.011 ± 0.14

12.612 ± 0.054

4.927 ± 0.017

25.496 ± 0.031

19.378 ± 0.192

Blank-SLN

21.929 ± 0.07

12.235 ± 0.032

4.401 ± 0.010

23.809 ± 0.150

17.025 ± 0.090

Blank-NLC

14.009 ± 0.04

7.332 ± 0.057

2.160 ± 0.059

17.602 ± 0.019

13.627 ± 0.367

TPL-SLN

14.181 ± 0.09

7.858 ± 0.016

3.261 ± 0.017

19.927 ± 0.723

15.798 ± 0.234

TPL-NLC

6.138 ± 0.08

3.198 ± 0087

0.875 ± 0.011

7.781 ± 0.075

5.822 ± 0.087

  1. νas CH2, asymmetric C–H stretching; νs CH2, symmetric C–H stretching; νs C=O, Carbonyl stretching; Amide I, C=O stretching and Amide II, C–N stretching and N–H bending