Table 1 Particle size and zeta potential of silymarin-loaded lipid-polymer hybrid nanoparticles (S-LPNs) and chitosan-modified S-LPNs (CS-LPNs) (n = 3)
Formulation | Particle size (nm) | Polydispersity index | Zeta potential (mV) | Encapsulation efficiency (%) |
|---|---|---|---|---|
S-LPN | 125.8 ± 7.8 | 0.142 ± 0.023 | − 43.1 ± 8.4 | 97.39 ± 0.01 |
CS-LPN | 286.5 ± 23.8 | 0.226 ± 0.008 | 45.3 ± 8.9 | 97.05 ± 0.01 |