Fig. 10

Survival rates of mice intraperitoneally injected with S. aureus (a), E. coli (b) and mixed S. aureus and E. coli bacteria (c). Animals in each bacterial infection model group (n = 24) were randomly divided into four groups (n = 6, three female mice and three male mice) and then intraperitoneally injected with 200 μL of saline, BA solution, polymyxin B, Nano-BA_PLGA or Nano-BA_P85 at doses of 100 mg/kg, 100 mg/kg, 30 mg/kg, 30 mg/kg and 30 mg/kg twice a day for 3 days. Data are expressed as the mean ± standard deviation based on the values obtained from the six mice in each group