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Fig. 2 | Journal of Nanobiotechnology

Fig. 2

From: Exosomes derived from siRNA against GRP78 modified bone-marrow-derived mesenchymal stem cells suppress Sorafenib resistance in hepatocellular carcinoma

Fig. 2

Isolation and Characterization of siGRP78 modified MSCs derived from human bone marrow. a Flow cytometric analysis showed BM-MSCs were positive for mesenchymal lineage markers (CD73, CD90 and CD105), negative for hematopoietic and endothelial markers (CD34, CD11b, CD19, CD45), and negative for HLA-DR. b Representative morphology of BM-MSCs. c Down-regulating the expression of GRP78 in BM-MSCs do not influence the stemness trait of MSC. Blue was the control siRNA; red was the siGRP78. d qPCR showed GRP78 was down-regulated in the siGRP78 transfected BM-MSCs compared with control siRNA (scramble siRNA)

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Journal of Nanobiotechnology

ISSN: 1477-3155

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