Fig. 4

In vitro and in vivo release of NE-P22. a In vitro release profile of NE-P22. b In vivo fluorescence imaging of FITC-labeled P22 in the mouse nasal cavity, relative fluorescence intensity recorded at 0, 0.5, 1, 4, and 8 h after nasal administration of NE-P22 or P22. c Quantitation of fluorescence intensity. The data are expressed as the mean ± SD (n = 3). *P < 0.05, ***P < 0.001