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Table 1 Composition and physicochemical characteristics of blank and drug-loaded BSA NPs

From: Combining hydrophilic chemotherapy and hydrophobic phytotherapy via tumor-targeted albumin–QDs nano-hybrids: covalent coupling and phospholipid complexation approaches

 

Formula

Particle size (nm)

Zeta potential (mV)

PDI

%RSV EE

%PMT CE

F1*

RSV/PMT-BSA NPs

142.8 ± 5.7

− 31.7 ± 1.5

0.158

65.33 ± 5.8

63.3 ± 2.1

F2

RSV/PMT-BSA-QDs NPs

154.8 ± 6.6

− 27.2 ± 1.1

0.202

67.34 ± 6.1

64.2 ± 2.3

F3

Mann-targeted RSV/PMT-BSA-QDs NPs

193.9 ± 4.8

− 33.1 ± 1.2

0.184

68.1 ± 5.1

50.9 ± 1.9

F4

Mann-targeted RSV/PMT-BSA NPs

155.5 ± 3.9

− 32.7 ± 1.4

0.117

65.2 ± 4.9

57.8 ± 3.6

  1. * All NPs were prepared using 100 mg PMT-BSA, RSV/PC complex eq. to 10 mg RSV, and 55 µl (8%v/v) glutaraldehyde as a cross-linking reagent
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Journal of Nanobiotechnology

ISSN: 1477-3155

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