Table 3 IC₅₀, Combination Index (CI) and Dose Reduction index (DRI) values of free RSV, free PMT and free RSV/PMT co-solvent compared to the prepared nano-formulations on MCF-7 breast cancer cell line at the concentration of 0–60 μg/ml after 24 h

Free RSV

–

–

22.24

–

–

–

Free PMT

–

–

–

17.21

–

–

Blank NPs

–

–

–

–

–

10,739

RSV/PMT

0.981

13.95

7.86

6.15

2.82

2.79

F1 [RSV/PMT-BSA NPs]

0.926

11.1

6.26

4.89

3.55

3.51

F2 [RSV/PMT-BSA-QDs NPs]

0.909

10.96

6.18

4.83

3.59

3.56

F3 [Mann-targeted RSV/PMT-BSA-QDs NPs]

0.813

9.17

5.17

4.04

4.30

4.25

F4 [Mann-targeted RSV/PMT-BSA NPs]

0.901

10.1

5.69

4.45

3.90

3.86