Environmental hazard assessment for polymeric and inorganic nanobiomaterials used in drug delivery

Table 1 Summary of the number of ecotoxicological endpoints found for the selected NBMs

NBM	Compartment	# Endpoints	# Species	# Taxonomic groups	# Endpoints on environmental organisms^a
Nano-chitosan	Freshwater	16	7	3	4
Nano-chitosan	Soil	0	0	0	0
Non-nano chitosan^b	Freshwater	138	25	5	5
Non-nano chitosan^b	Soil	60	8	2	0
Nano-HAP	Freshwater	13	6	3	8
Nano-HAP	Soil	1	1	1	0
Non-nano HAP	Freshwater	0	0	0	0
Non-nano HAP	Soil	0	0	0	0
PAN nanofibers	Freshwater	2	1	1	0
PAN nanofibers	Soil	1	1	1	0
Non-nano PAN	Freshwater	0	0	0	0
Non-nano PAN	Soil	0	0	0	0
Nano-PLGA	Freshwater	0	0	0	0
Nano-PLGA	Soil	0	0	0	0
Non-nano PLGA	Freshwater	0	0	0	0
Non-nano PLGA	Soil	0	0	0	0
Nano-PLA	Freshwater	0	0	0	0
Nano-PLA	Soil	0	0	0	0
Non-nano PLA	Freshwater	0	0	0	0
Non-nano PLA	Soil	0	0	0	0
Nano-PHA	Freshwater	0	0	0	0
Nano-PHA	Soil	0	0	0	0
Non-nano PHA	Freshwater	0	0	0	0
Non-nano PHA	Soil	0	0	0	0

^aEnvironmental organism stands for all species except for pathogenic bacteria and fungi
^bDissolved

ISSN: 1477-3155