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Table 1 Summary of all differentially regulated genes involved in the maintenance of intestinal epithelial cells integrity

From: Alteration in the mRNA expression of genes associated with gastrointestinal permeability and ileal TNF-α secretion due to the exposure of silver nanoparticles in Sprague–Dawley rats

Gene

Family

Females

Males

10 nm AgNP

110 nm AgNP

AgOAc

10 nm AgNP

110 nm AgNP

AgOAc

Cav1

Focal adhesions

    

Cav2

Focal adhesions

     

Cldn1

Tight junctions

     

Cldn10

Tight junctions

     

Cldn15

Tight junctions

  

   

Cldn5

Tight junctions

     

Cldn6

Tight junctions

     

Cldn9

Tight junctions

  

   

Dsg4

Desmosomes

     

Dst

Hemidesmosomes

     

Gja3

Gap junctions

  

   

Icam1

Tight junctions

     

Itga8

Focal adhesions

     

Itgal

Focal adhesions

  

   

Itgb2

Focal adhesions

     

Notch1

Adherens junctions

     

Notch2

Adherens junctions

     

Notch3

Adherens junctions

  

   

Notch4

Adherens junctions

  

   

Ocln

Tight junctions

     

Pecam1

Tight junctions

     

Pvrl1

Adherens junctions

     
  1. This table shows significant (p ≤ 0.05) alterations across all treatment groups as compared to its respective controls