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Fig. 1 | Journal of Nanobiotechnology

Fig. 1

From: Lipid–peptide bioconjugation through pyridyl disulfide reaction chemistry and its application in cell targeting and drug delivery

Fig. 1

Two-step lipid–peptide conjugation through pyridyl disulfide reaction chemistry. Lipid activation (Step 1, left) DPTE lipid is activated with mercaptopyridine to avoid non-specific unwanted reaction products, i.e. the formation of the symmetric DPTE disulfide. Lipid bioconjugation (Step 2, right): the activated DPTE react with the sulfhydryl-group of the peptide of interest

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