Fig. 1

Exosome-mimetic nanoplatforms characterization. a Hydrodynamic size (Z-average) of EMNs measured by dynamic light scattering (DLS) under storage conditions (4 °C) and b in culture media and human plasma, over the time (from t = 0 to 120 days, 5 h and 20 h, respectively; n = 6). c Hydrodynamic size measured by DLS of 19 independent batches of EMNs (green dots); horizontal bar represents mean ± SD. d ¹H-NMR spectrum showing representative signals of each component found in intact (D₂O) and broken EMNs (MeOD) compared to the spectrum of the pure components (PC, SM, and CH). Specific peaks of each component identified in the sample of broken EMNs were highlighted with colored rectangles (PC, yellow rectangles; SM, red rectangles; CH, purple rectangles)