Fig. 8

a Cytotoxic effect of miR-139 combined with afatinib in various formulations and b transfection efficiency of FAM-miR139/LPN-HR and other transfection reagents in Caco-2 cells. Values are the mean ± SD (n = 3). For a *P < 0.05: compared with CTR, ^†P < 0.05: compared with Afa, ^‡P < 0.05: compared with Afa/LPN-HR, ^¶P < 0.05: compared with miR-139 by Student’s t-test. NC was as a negative control. For b *P < 0.05: compared with CTR, ^†P < 0.05: compared with T-pro, ^‡P < 0.05: compared with PolyJet, ^¶P < 0.05: compared with Lipo 3000 by Student’s t-test