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Fig. 1 | Journal of Nanobiotechnology

Fig. 1

From: Magnetic targeting of adoptively transferred tumour-specific nanoparticle-loaded CD8+ T cells does not improve their tumour infiltration in a mouse model of cancer but promotes the retention of these cells in tumour-draining lymph nodes

Fig. 1

Evaluation of MNP toxicity and uptake by OT-I CD8+ T cells. a Cell viability of OT-I CD8+ T cells after treatment with MNPs, measured using the Alamar Blue fluorometric test. b Analysis by flow cytometry of the percentage of apoptotic or necrotic OT-I CD8+ T cells after incubation with MNPs by Annexin V/PI staining. c Quantification by ICP-OES of the iron associated with the OT-I CD8+ T cells after incubation with the different MNPs. Mean values ± SD are shown for three different experiments, *p < 0.05, **p < 0.01, ***p < 0.001

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Journal of Nanobiotechnology

ISSN: 1477-3155

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