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Fig. 1 | Journal of Nanobiotechnology

Fig. 1

From: Dynamic profiles, biodistribution and integration evaluation after intramuscular/intravenous delivery of a novel therapeutic DNA vaccine encoding chicken type II collagen for rheumatoid arthritis in vaccinated normal rodent

Fig. 1

Persistence of CCOL2A1 gene in peripheral blood from vaccinated normal rats. pcDNA-CCOL2A1 was intramuscularly injected into normal Wistar rats with a single dose of 300 μg/kg (N = 6). Peripheral blood samples were continuously harvested at various time points and processed for qPCR determination. Data are expressed as PCN/μg RNA; LOD = 200 PCNs/μg RNA and LLOQ = 1000 PCNs/μg RNA. “PCNs” represent “plasmid copy numbers”. *P < 0.05 compared with the value of 0 d using the t-test

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Journal of Nanobiotechnology

ISSN: 1477-3155

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