Fig. 6
From: Isolation of microglia-derived extracellular vesicles: towards miRNA signatures and neuroprotection
Analysis of neuronal proteome under the influence of microglial EVs. a Venn diagrams showing common and exclusive proteins between neurons treated with either 106 or 107 microglial EVs (P2-EV+) and neurons treated with P3-EV‒ (control). b The Perseus software generates heatmaps of common proteins showing only clusters of significantly over-represented proteins in EV-activated neurons (blue frame) and control condition (yellow frame). c, d Gene Ontology (GO) analysis of biological pathways (c) and cellular components (d) from exclusive and over-represented proteins in EV-activated neurons (shades of blue) vs. control (shades of yellow). The values are represented in percentage of total proteins for each condition