Fig. 4

Tumor targeting ability of THLG-EXO in a nude mouse xenograft model using HCT-116^5FR cells. a In vivo fluorescent images of HCT-116^5FR-bearing nude mice after intravenous injection of DiR-labeled THLG-EXO (left panel) or LG-EXO (right panel). b Quantitative analysis showed the relative fluorescence intensities in the tumor region (upper panel) and the liver (lower panel) following administration of THLG-EXO or LG-EXO. Data were expressed as means ± SD. n = 5; *P < 0.05, **P < 0.01 versus the LG-EXO group at the same time point