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Fig. 10 | Journal of Nanobiotechnology

Fig. 10

From: Iron oxides nanoparticles (IOs) exposed to magnetic field promote expression of osteogenic markers in osteoblasts through integrin alpha-3 (INTa-3) activation, inhibits osteoclasts activity and exerts anti-inflammatory action

Fig. 10

IOs and MF increase MC3T3 differentiation. Representative photographs from OPN staining (A) and its relative expression established by qRT-PCR (B). Additionally, expression of master regulators of osteogenic differentiation: BMP-2 (C), ALP (D), Coll-1 (E), OCN (F), DMP-1 (G) and SOST (H) was investigated. Results expressed as mean ± SD. Statistical significance indicated as asterisk (*) when comparing the results between corresponding bars representing MF− and MF+ groups, and as number sign (#) when comparing to CTRL MF−. #p < 0.05; ##, **p < 0.01; ###, ***p < 0.001

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