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Fig. 7 | Journal of Nanobiotechnology

Fig. 7

From: Drug affinity and targeted delivery: double functionalization of silk spheres for controlled doxorubicin delivery into Her2-positive cancer cells

Fig. 7

Confocal microscopy of the intracellular distribution of Dox-loaded silk spheres. (a, b) SKBR3 and (c, d) MSU1.1 cells were incubated at 37 °C for 15 (a, c) and 30 (b, d) min with Dox-loaded H2.1MS1:DOXMS2, H2.1MS1:MS2, and MS1:DOXMS2 spheres. DAPI: the nuclei stained with DAPI (blue); Dox: Dox-loaded spheres and Dox released from the spheres (red); merge: the colocalization of the nuclei and Dox. The scale bar represents 10 μm

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