Fig. 11

Effects of DPM on ICH-induced apoptosis and ferroptosis. a Representative Western blots of GPX-4, Bcl-2, Bax, and caspase-3 in the left hemisphere of at 24 h after ICH and treatment with nothing (sham), 0.9% saline (vehicle), free dauricine (DRC), empty micelles (PM) or dauricine-loaded micelles (DPM). Results are representative of three experiments. Levels of b GPX4 and Bcl-2 as well as c Bax and caspase-3 were quantitated relative to β-actin, and levels are expressed relative to that in the sham group. Values are mean ± SD, n = 3. *P < 0.05