Fig. 8From: Metal ion-responsive nanocarrier derived from phosphonated calix[4]arenes for delivering dauricine specifically to sites of brain injury in a mouse model of intracerebral hemorrhageDistribution of DiR-labeled empty micelles (DiPM) in ICH mice, assessed at 12 and 24 h after tail vein injection into mice with ICH. Key organs were removed and examined using an IVIS system. a DiPM accumulated at the hemorrhagic site at much higher level than free DiR. Images show the fluorescence intensity as an overlay in accordance with the scale. b Quantitation of DiR and DiPM in brain at 12 and 24 h after injection. **P < 0.01 (n=3)Back to article page